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John Dough
06-30-22, 21:41
https://www.prnewswire.com/news-releases/preliminary-phase-ii-data-show-ahcc-supplementation-may-support-the-host-immune-system-to-eradicate-the-human-papilloma-virus-hpv-in-women-300743977.html

Mushroom Extract May Eradicate Human Papilloma Virus in Women.

November 5, 2018.

Preliminary results from one of the presentations made at the recent Society for Integrative Oncology 15th international conference in Scottsdale, Arizona, showed that daily supplementation with AHCC could support the host immune system to eradicate Human Papilloma Virus (HPV) infection in women.

The randomized, double-blind, placebo-controlled study is following 50 women for up to 12 months, with one group taking six capsules, each containing 500 milligrams of AHCC, and a second cohort receiving placebo.

The results showed that at six months, 58.8 percent of the patients taking AHCC showed no signs of the infection. In the placebo group, one patient showed no signs of the infection at three, six, 9 and 12 months of study. AHCC was well-tolerated in patients who received it.

"There currently is no standard of care for persistent, high-risk HPV infections so we have been taking a systematic approach over the past 10 years with our research. We have studied AHCC from bench studies and two pilot studies that supported rationale for our current ongoing phase II clinical trial to evaluate AHCC supplementation to support the host immune system to clear persistent HPV infections".

AHCC (Active Hexose Correlated Compound) is a natural immune-modulating compound derived from a unique fraction of specially-cultured medicinal mushroom mycelia (roots) which has been clinically proven to modulate the immune system. AHCC is supported by more than 30 human clinical studies and more than 50 papers in PubMed-indexed journals.

Studies indicate that AHCC works as an immunotherapy by using the body's own immune system to help fight disease. Human and pre-clinical studies have shown that AHCC increases the number and / or activity of natural killer (NK) cells, killer T-cells, dendritic cells, and cytokines, which enable the body to effectively respond to infections.

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6435520/

From Bench to Bedside: Evaluation of AHCC Supplementation to Modulate the Host Immunity to Clear High-Risk Human Papillomavirus Infections.

Pre-clinical in vitro and in vivo studies demonstrated durable clearance of HR-HPV infections. The preliminary data from the two pilot studies suggested that AHCC supplementation supports the host immune system for successful clearance of HR-HPV infections. A confirmatory phase II randomized, double-blinded, placebo-controlled study is ongoing.

The presented bench-to-bedside research provides step-wise data to support the hypothesis that AHCC supplementation modulates host immune system, specifically via suppression of elevated IFNβ levels, to effectively clear chronic, persistent HR-HPV infections. After observing elimination of HR-HPV in vitro in the panel of human cervical cancer cell lines, animal studies were completed that also demonstrated successful, durable elimination of HR-HPV after completing AHCC supplementation. Finally, in two "proof of concept" pilot studies of daily AHCC supplementation successful elimination of HR-HPV was achieved that was durable response. Both the animal and human data suggests the mechanism AHCC supplementation supports the host immune system to clear HPV infections is attributed to the modulation of the expression and signaling of IFNβ that is known to be elevated in chronic viral infections.

John Dough
06-30-22, 22:14
https://www.drweil.com/health-wellness/body-mind-spirit/colds-flu/new-weapon-against-colds/

"Laboratory studies show that olive leaf extract can suppress a number of viruses, including those that cause the common cold. Oleuropein, the extract, is a bitter substance removed from olives during processing. In animal experiments the compound has been well-tolerated with no serious adverse effects. It has been reported to increase natural killer cell function and to be effective against viruses like HIV, hepatitis B and C, and herpes".

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3002804/

"Oleuropein has several pharmacological properties, including antioxidant, anti-inflammatory, anti-atherogenic, anti-cancer, antimicrobial, and antiviral, and for these reasons, it is commercially available as food supplement in Mediterranean countries.

"Antimicrobial effect: Oleuropein has been shown to have strong antimicrobial activity against both Gram-negative and Gram-positive bacteria as well as mycoplasma. Recently, Sudjana et al showed the antimicrobial activity of commercial Olea europaea (olive) leaf extracts (abundantly oleuropein) against methicillin-resistant Staphylococcus aureus (MRSA)".

"Antiviral effect: The olive leaf extracts were investigated for their antiviral activity against HIV-1 infection and replication. Cell-to-cell transmission of HIV was inhibited in a dose-dependent manner, and HIV replication was inhibited in an in vitro experiment".

John Dough
06-30-22, 23:01
https://www.drweil.com/health-wellness/body-mind-spirit/sexual-health/halting-herpes/

"Monolaurin is a nontoxic, antiviral supplement made from lauric acid (a fatty acid found in breast milk and coconut oil) and glycerin. It is used to treat infections with all strains of the herpes virus along with other viral infections including measles, and HIV, the human immunodeficiency virus that causes AIDS. Monolaurin is believed to have the potential to permanently inactivate the fat coated viruses that cause these diseases by fluidizing the lipids (fats) and phospholipids in their envelopes, leading to the disintegration of viral particles".

https://www.westonaprice.org/health-topics/ask-the-doctor/herpes/

"I have been consistently impressed with the ability of Lauricidin (a brand of monolaurin supplement) to suppress herpes outbreaks, and allow people to get off their antiviral drugs".

https://www.monolaurinandmore.com/articles/monolaurin-hsv

"Herpes is a DNA virus which belongs to the family Herpesviridae which include Varicella (chicken pox), Zoster (shingles), EpsteinBarr (mono), and Herpes Simplex Virus (cold sores and genital herpes). These viruses are "enveloped", which means the virus has a lipid or fatty capsule around the DNA which enables the virus to have a chronic impact on the nervous system".

"Monolaurin has been shown in laboratory studies to break down the fatty envelope which protects enveloped viruses, which in turn inactivates the virus and inhibits the replication of the virus. This laboratory research has been replicated through multiple studies".

https://www.myfoodresearch.com/uploads/8/4/8/5/84855864/_67__fr-2020-324_subroto.pdf

"Monolaurin is known to be able to enhance the immune system through modulation of various immune systems, controlling pro-inflammatory cytokines, activating and attracting leukocytes to the site of infection. Monolaurin can also act as an antiviral, especially against enveloped viruses, such as Maedi-visna virus, vesicular stomatitis, herpes simplex-1, measles, HIV, cytomegalovirus, influenza, and corona. Monolaurin inhibits the virus through the mechanism of the disintegration of the viral membrane, prevents binding of the viral protein to the host-cell membrane, inhibits the process of assembling the viral RNA, and the process of virus maturation in the replication cycle. Therefore monolaurin has the potential for human consumption to boost the immune system and ward off various virus attacks, including severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2), which is the cause of COVID-19 which became a pandemic in the world".

https://jamaica-gleaner.com/gleaner/20110927/news/news7.html

"Butylated HydroxyToluene (BHT) is a synthetic food preservative that is widely used in breakfast cereals, baked goods, potato chips, sausage, peanut butter and other commercial foods. It is a very non-toxic substance that has many outstanding effects including the destruction of the herpes virus. BHT inactivates the herpes virus by disrupting its lipid shell, leaving it exposed and vulnerable to attack by the immune system. BHT is also effective against shingles, hepatitis, influenza and other viral diseases and is available in capsule form".

Sammon
06-30-22, 23:12
Most of us I am sure come down with cold, cough, sore throat in our hobby. I strongly recommend chewing on zinc lozenges which prevents these. Do it several times a day.

John Dough
06-30-22, 23:32
https://anh-usa.org/herpes-why-is-conventional-medicine-ignoring-the-obvious-solution/

"Herpes. Why is Conventional Medicine Ignoring the Obvious Solution"?

"Vitamin D is a powerful natural antiviral. Research from the University of Copenhagen shows that vitamin D activates the immune system by arming T-cells to fight off infections. Without vitamin D, the immune system's T-cells remain dormant, offering little or no protection against invading microorganisms and viruses. Japanese study found that vitamin D was more effective than a vaccine in preventing flu. School children taking vitamin D were 58 percent less likely to catch influenza A. By contrast, antiviral drugs such as oseltamivir (Tamiflu) and zanamivir (Relenza) reduced rates of infection by only 8 percent. Even vaccines had success rates significantly lower than the 58 percent achieved by vitamin D. The problem is that a whopping 59 percent of the population is deficient in vitamin D. For anyone plagued by herpes, it's essential that you are getting enough vitamin D. Optimal levels should be between 50 to 80 ng / ML, year-round. Take a vitamin D supplement (be sure it's D3 cholecalciferol), get your blood retested to verify that you're taking the proper dosage, and get sufficient exposure to the sun".

https://healthimpactnews.com/2018/vitamin-d-more-effective-than-pharmaceutical-drugs-in-treating-herpes-virus/

"Vitamin D More Effective than Pharmaceutical Drugs in Treating Herpes Virus".

"Half of teens and adults under the age of 50 are infected with the oral herpes virus, and one in eight has genital herpes. Despite the prevalence of herpes, public health authorities ignore a cheap, safe, and effective treatment for this common infection, and instead rely on expensive medicines that do not treat the underlying problem".

"One study found that dialysis patients who receive vitamin D were less likely to develop shingles, which is part of the herpes family of viruses; higher vitamin D levels corresponded with more antibodies to the herpes-simplex-2 virus. Vitamin D works best when other cofactors are present, such as magnesium, vitamin K2, zinc, boron, and vitamin A".

"Our vitamin D mediated immune response has been with us through more than 60 million years of pre-human and human evolutionary selection, as research from Ohio State demonstrates. Vitamin D is critical to our survival".

John Dough
07-01-22, 00:36
https://journals.lww.com/stdjournal/fulltext/2008/03000/Probiotics__Potential_to_Prevent_HIV_and_Sexually.2.aspx

"Probiotics: Potential to Prevent HIV and Sexually Transmitted Infections in Women".

"Women are at significant risk of human immunodeficiency virus (HIV) and sexually transmitted infection (STI) acquisition with the genital mucosa serving as the main portal of infection. Exogenously supplied lactobacillus used as a probiotic may prove a cost-effective, female-initiated method to prevent HIV and STI infection in women. A probiotic may act indirectly through treating and preventing recurrent bacterial vaginosis (BV) or directly by secreting endogenous (e. G. , hydrogen peroxide) and exogenous substances that block HIV and STI transmission. Increased HIV, trichomonas, gonorrhea, chlamydia, and herpes simplex virus (HSV) infections have been associated with BV. Prevention of BV may therefore reduce the incidence of more than 1 STI".

https://invisiverse.wonderhowto.com/news/vaginal-probiotics-could-slow-zika-other-std-infections-0178928/

"Vaginal Probiotics Could Slow Zika & Other STD Infections".

"New research has shown that vaginal bacteria can inhibit sexually transmitted Zika virus and Herpes Simplex Virus-2 in women. Bacterial vaginosis is an infection where the hallmark characteristic is replacement of Lactobacillus by a mixture of different bacteria. Human Papilloma Virus (HPV) infection, cervical pre-cancer, and the development of cervical cancer have been linked to an increased diversity of vaginal bacteria, combined with a reduced abundance of Lactobacillus. Herpes Simplex Virus-2 increased when grown in cultures lacking Lactobacillus".

https://journals.asm.org/doi/pdf/10.1128/iai.49.2.320-324.1985

"Lactobacilus casei GR1 taken from the urethra of a healthy woman was incorporated into agar beads, instilled within the rat bladders before challenge with uropathogens instilled into the urinary bladder. Our results show that L. Casei prevented onset of urinary tract infection in 84% of the animals tested. The lactobacilli appeared to exclude the uropathogens from colonizing the urinary tract, within the first 48 hours after challenge, and the net effect was a complete eradication of bacteria from the uroepithelium".

John Dough
07-01-22, 01:04
https://www.wellbeingjournal.com/cancer-hivaids-reversed-with-selenium-amino-acids/

"Taken as a whole, the geographical evidence, therefore, strongly suggests that selenium is protective against HIV infection. Such a relationship is not limited to this virus. Field trials in China also have shown that hepatitis B and C viral infection rates can be reduced by selenium supplementation. Selenium supplements can improve the human immune system by causing an increase in the enzyme glutathione peroxidase and in the production of interferon gamma and T helper cells and an earlier peak in T cell proliferation".

"Simply put, humans, animals and insects that are selenium deficient are easily infected by a wide variety of viruses. Those eating selenium-adequate diets are not. This relationship between the trace element and HIV is the key to reversing the current AIDS pandemic since it is the virus's Achilles' heel".

https://www.liverdoctor.com/selenium-the-immune-system-mineral/

"Selenium is the most important mineral for the immune system and the liver to function at their optimal level; indeed without adequate selenium in your body, your immune system and liver will remain vulnerable to attack. It's amazing to think that despite the profound importance of selenium to human health many people remain deficient in this life saving mineral".

"Selenium deficiency is a widespread and serious problem in people of all age groups from the very young to the very old. Unfortunately there is a misconception that selenium deficiency rarely occurs in developed countries. However studies have shown that selenium deficient soils exist in large areas of the USA, New Zealand and Australia and dietary intake of selenium is steadily decreasing in many European countries".

"Research has shown that men consuming the most dietary selenium develop 65% fewer cases of advanced prostate cancer than men with the lowest selenium intake".

"What are the consequences of selenium deficiency"?

Higher morbidity rates in people with chronic viral hepatitis.

Higher morbidity and mortality rates in people with AIDS.

Higher viral loads.

Increased incidence of many different types of cancer.

Frequent colds and flu.

Increased susceptibility to infections of all types.

Persistent infection of the cervix with the human papilloma virus (HPV).

Incurable warts on the skin or genitals.

Severe and / or recurrent infections with the herpes virus cold sores, genital herpes and shingles.

John Dough
07-01-22, 01:36
https://jamaica-gleaner.com/gleaner/20110927/news/news7.html

"A strong and healthy immune system is our main defence against any kind of disease. Many people come in contact with herpes but never contract it because of their efficient immune systems. Nutrients can have a direct stimulatory effect on the immune system. These include the antioxidants. The ACES: Vitamin A, Vitamin C, vitamin E and Selenium. Vitamin B12 is another important nutrient with anti-herpes properties".

https://www.dynamicchiropractic.com/mpacms/dc/article.php?id=53184

"Broccoli, brussels sprouts, cabbage, cauliflower and bok choy contain an active ingredient known as the indole-3-carbinol, which has been shown to inhibit replication of herpes viruses. The levels of vitamin C, selenium, zinc, vitamin A, beta-carotene and vitamin E in a high-potency multivitamin can enhance immune function, which has been reported to suppress herpes. Reishi mushroom extract has been shown to possess potent antiviral properties against HSV-1 and HSV-2".

https://www.sciencedaily.com/releases/2012/08/120827122258.htm

"A new study suggests that nicotinamide (niacinamide), more commonly known as vitamin B3, may be able to combat some of the antibiotic-resistance staph infections and "superbugs" that are increasingly common around the world, have killed thousands and can pose a significant threat to public health. The research found that high doses of this vitamin increased by 1,000 times the ability of immune cells to kill staph bacteria".

"It's a way to tap into the power of the innate immune system and stimulate it to provide a more powerful and natural immune response".

"The scientists found that clinical doses of nicotinamide increased the numbers and efficacy of "neutrophils," a specialized type of white blood cell that can kill and eat harmful bacteria. The nicotinamide was given at megadose, or therapeutic levels, far beyond what any normal diet would provide -- but nonetheless in amounts that have already been used safely in humans, as a drug, for other medical purposes".

John Dough
07-06-22, 01:59
https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2277319/

"Zinc affects multiple aspects of the immune system. Zinc is crucial for normal development and function of cells mediating innate immunity, neutrophils, and NK cells. Macrophages also are affected by zinc deficiency. Phagocytosis, intracellular killing, and cytokine production all are affected by zinc deficiency. Zinc deficiency adversely affects the growth and function of T and B cells".

https://immunityageing.biomedcentral.com/articles/10.1186/1742-4933-6-9

"The trace element zinc is essential for the immune system, and zinc deficiency affects multiple aspects of innate and adaptive immunity. Many studies confirm a decline of zinc levels with age. Even marginal zinc deprivation can affect immune function. Consequently, oral zinc supplementation demonstrates the potential to improve immunity. These data indicate that a wide prevalence of marginal zinc deficiency in elderly people may contribute to immunosenescence".

https://www.frontiersin.org/articles/10.3389/fimmu.2020.01712/full

"The most common symptoms of COVID-19 are impaired smell and taste, fever, cough, sore throat, general weakness, pain as aching limbs, runny nose, and in some cases diarrhea. In the subsequent chapters, we will associate most of those symptoms with altered zinc homeostasis and explain how zinc might prevent or attenuate those symptoms and thus should be regarded as promising cost-effective, globally available therapeutic approach for COVID-19 patients, for which minimal to no side effects are known. The World Health Organization (WHO) assumes that at least one third of the world population is affected by zinc deficiency. Zinc deficiency is responsible for 16% of all deep respiratory infections world-wide".

"As a virus, SARS-CoV2 is highly dependent on the metabolism of the host cell. Direct antiviral effects of zinc have been demonstrated in various cases, which was reviewed in great detail. Examples include coronaviridae, picornavirus, papilloma virus, metapneumovirus, rhinovirus, herpes simplex virus, varicella-zoster virus, respiratory syncytial virus, human immunodeficiency virus (HIV), and the hepatitis C virus. It was suggested that zinc can prevent fusion with the host membrane, decreases the viral polymerase function, impairs protein translation and processing, blocks viral particle release, and destabilizes the viral envelope".

https://bmcoralhealth.biomedcentral.com/articles/10.1186/s12903-020-01277-2

"Recurrent herpes labialis (RHL) is a common recurrent infective vesiculoulcerative disease. Topical and systemic administration of Zinc compounds has been indicated to have preventive and therapeutic effects. The results of this study indicate that, zinc deficiency can be considered as a risk factor for increasing the duration of herpes labialis lesions. Therefore, the evaluation of serum zinc level in the subjects with RHL and subsequent administration of zinc are recommended in these kind of patients".

Spider56
12-22-22, 23:17
Vitamin see is best.

John Dough
12-01-23, 23:47
https://vitamindwiki.com/50+ng+level+of+Vitamin+D+proven+to+fight+many+diseases+-+Whittle+May+2023

"Many peer-reviewed research articles conclusively demonstrate that a low level of 25-hydroxyvitamin D in the bloodstream significantly increases the risk of severe disease. Many types of immune cells rely on a suitably high level of 25-hydroxyvitamin D in the bloodstream. In 2008,48 leading vitamin D researchers called for the standard of vitamin D repletion to be 40 to 60 ng / ML of circulating 25-hydroxyvitamin D".

"These researchers' 50 ng / ML target has been vindicated by a large body of research, one strong example being the 2014 research of doctors in a Boston hospital on the risk of both hospital-acquired and surgical site infections, as a function of pre-operative 25-hydroxyvitamin D levels. What they found was striking. Their graphs (below combined into one) are easily understood".