Viagra

[Wapec]

Joe

Interesting research, findings and every monger that uses has a responsibility to themselves of being aware of any and all risks - from medical to physical health risks. For the benefit of others out there, this info is actually on the warnings avail written inside the box for vit V & C. Vit L I can't say as I've never used. The wording is not helpful for the non-wary but it is there. For example, vit V warns of possible general muscle soreness and prolonged dizziness in some which I've experienced and is why I personally use vit V. Similar to Joe I use vit C because it stays in the blood stream longer and it call also be flushed out of the body by excessive electrolytic fluids.

I believe that Joe has hit it on the button with his observation over daily use. None of these enhancers are designed for daily non-prescribed or daily use in men of any age. No study would ever be designed to cover say a group of mongers with prolonged usage. However, in small concentrated situations there increased risk levels would not be material or significant. This is one reason why I try to limit my activities to a week of wildness every couple of months. Of course, this also suits my natural rythmn between work and other commitments.

Not preaching in any way and each to their own.
/W

Did a bit more reading as directed by the info provided by Weelock and found out that these drugs do definitely dramatically increase the risk of going BLIND. Cialis is actually worse (25 times risk increase) than Viagra (18 times increase) as far as going NAION blind is concerned.
Let me see if I can find out the increased risk of death by using these drugs.
SEAJ

[Petemcc]

Hey Pete:

I believe that you are a male nurse? If so, can you please double check your above statement with some of the doctors you must have daily contact with?

You see, a very good friend of mine, early 50'S, in previous good physical shape (a full medical check up at Bumrungard a year or so ago only reveal a bit elevated Cholesterol level - close to borderline), VERY careful with his diet and fastidious in his hygiene - just had a heart attack and died.

The only thing that I can think of is that he did have a one a day habit - i.e. he would pop one gal per day and to do so, he took Viagra daily. The V was prescribed by his doctor in the States (genuine) and thus no problem with purity etc.

I read your statement about Pfizer and how they must be pretty sure etc - but we all know some of the horror stories with these drug companies and how they would "do things" just to keep sales up.

The question is - is Viagra really that safe? And safe for DAILY use?
I know I know, anything done to an excess is no good - but really - if a guy wants a daily pop - is it really all that excessive?

Secondary question - since Ciallis keeps me "ready to go'' for at least a couple days - sometimes even 3 days - is it safer than viagra which requires dosage every 5 or so hours? In that my friend would probably have needed only a dose every few days instead of daily?

Thanks Pete - and whoever else who could contribute their own knowledge etc on this matter

Ciao
SEAJ

Guys
I only just got PMd about this thread, and a about to go to bed. Understand that I am not an expert, however with my training and background, I am able to critically review literature, and I will do this.
I don't know if I have said this before, but there is no such thing as a safe drug, someone, somewhere will have a problem with a drug.
Also, I have always said, do not self medicate. Use a GP, they can at least monitor what is going on-OK, it's more expensive, but initially.

I will do some research and post it all, but one important thing to remember in the meantime is IF YOU ARE ON NITRATES, DO NOT USE ED DRUGS.
You will be on nitrates if you have or have had angina.
Note also, amyl nitrate is a nitrate, and some younger guys pop this as well.
Briefly, the platelet research is interesting, if correct-answer, half an aspirin a day, but fuck me, they can't have it both ways, it's a dilator yet constrictions are blocked by platelets?
Also heart attacks (myocardial infarctions) are caused when there is not enough blood to areas of the heart muscle. This is nearly always caused by a blockage in a coronary artery. Yes, very low blood pressure can have the same effect, and some people do naturally have very low blood pressure, or take recreational drugs which lower BP.
Finally, before I go, researchers these days seldom find things by chance, because they are paid to find specifics, or they work on personal hunches and acquire funding, so there may be hidden agendas, then again, there may not.
I suspect more people will die from aspirin every year, which is in itself a wonder drug and keeps post heart attack victims alive for one, than will ever die from ED drugs.

Watch this space.
Pete

[XXL]

Sorry to hear Viagra could be bad for your heart. Because of its blood-pressure lowering properties, it has been used by users of stimulants (Xstasy, coke) to guard against hypertensive crises.

The side-effects on eyesight (and maybe on the eye) are well established.

For those who are interested, I ordered PT-141 (bremelanotide) from China. Difficult to feel an effect. Concentrations are probably not sufficient.

[SE Asia Joe]

and this from psa rising - a prostrates cancer survivor support group
seaj
ps. i've rtff'd this thread, going back 21 pages and except for petemcc's reference which i had earlier quoted, i could not find any discusssions on the safety of these ed drugs. has there been any discussions on this thread on this?? anybody recall?

viagra may cause heart attack deaths in younger men with no heart problems, study finds
march 14, 2000. viagra, commonly prescribed by doctors to treat male erectile dysfunction, is turning up too often at the scene of heart attack death in relatively young men. some men may be vulnerable to heart attack after taking this drug, made by pfizer. that is not known, but the drug itself is beginning to look like more than a bystander in the deaths.

some men who have died after taking viagra were elderly and on heart medication. but a study reported march 14 finds that more men who have died were **** sixty-five. most of the deaths have occurred within a few hours of taking the drug. most of the men took the standard dose. most of the men had no reported heart problems. although some men who died were taking nitrates as well as viagra, men who were not taking nitrates died at a higher rate.

this new evidence comes from post-marketing adverse event reports about viagra made to the fda. researchers at cedars-sinai medical center in los angeles analyzed these reports and found that there "appears to be a high number of deaths and serious cardiovascular events associated with the use of viagra." they presented the study march 14 at the meeting of the american college of cardiologists in anaheim, ca.

in an analysis of 1,473 major adverse events recorded in these reports about viagra to the fda, 522 people died, most of them from cardiovascular causes. according to the study's senior author, dr. kaul, the majority of deaths were associated with standard viagra dosages (70 percent of the deaths were associated with the 50 mg dose). the deaths were due to cardiovascular causes and appeared to be clustered around the time of dosing (two thirds of deaths in which the time from ingestion to death was reported, occurred within 4-5 hours of taking viagra). the majority of deaths occurred in patients who were less than 65 years of age, and who had no reported cardiac risk factors.

the study confirmed the well-documented increased risk with combined use of nitrates and viagra. of 90 patients who suffered major heart events while taking viagra on top of nitrates, death occurred in about 68 percent, and when myocardial infarction was counted, the number of major cardiovascular events in that group rose to 88 percent.

however, the study found that most deaths (88 percent) actually occurred in patients who were not taking nitrates, leading investigators to speculate whether there are some susceptible individuals who don't need nitrates to unmask the harmful effects of viagra.

[SE Asia Joe]

How Viagra possibly causes the onset of a heart attack.

(With due apologies if I perhaps am putting a damper on your enthusiasm for our "Activities" aided by these drugs.
Sorry guys, really, but the death of my friend has really gotten to me.)
SEAJ

Saturday, 11 January, 2003, 00:00 GMT
Clue to mystery Viagra deaths


Viagra has been linked to a number of deaths

The mystery behind the deaths of a small number of men taking the anti-impotence drug Viagra may have been solved by scientists.
Although Viagra has achieved worldwide renown as a highly effective treatment for impotence, it was originally developed to prevent heart attacks and strokes.

Our research suggests Viagra may present a risk for patients with pre-existing conditions



Professor Xiaoping Du

The drug was thought to work not only by dilating the blood vessels, but also by stopping tiny solid particles in the blood called platelets from clumping together and forming clots that could block blood flow and trigger a heart attack or stroke.

However, new work by researchers from the University of Illinois at Chicago has found that the drug in fact has the reverse effect - it stimulates the clumping of platelets, thus raising the risk of clotting.

Lead researcher Professor Xiaoping Du said: "Viagra, by itself, probably is not sufficient to cause a heart attack in healthy people, but our research suggests that it may present a risk for patients with pre-existing conditions such as atherosclerosis."

Effect on cells

The researchers tested the effect of Viagra on platelets taken from normal donors.

Alone the drug did not stimulate the platelets to stick together.

But it did if other compounds found in the bloodstream when the blood vessels are damaged - such as when somebody is suffering from heart disease - were added.

In fact, under these conditions Viagra caused the platelets to clump together at concentrations well below those found in patients prescribed the drug as an impotence treatment.

Viagra acts on platelets by inhibiting the breakdown of a compound found in cells called cyclic guanosine monophosphate (cGMP).

For 20 years scientists have thought cGMP acts to stop platelet clumping.

But the Chicago researchers believe that in fact cGMP initially causes platelets to clump together to seal a wound, only later reversing its effect to stop an excessive build-up that might block a blood vessel.

In most circumstances, they argue this would work well.

But a person at risk may already have blood vessels narrowed to the point that even the initial clumping of platelets could be enough to cause problems.

Safety record

Joel Morris, a spokesman for Pfizer, which makes Viagra, told BBC News Online that the drug had been shown to have a very impressive safety record.

"We take this research seriously, and it will be scrutinised by our medical teams.

"But a recent study by the Drug Safety Research Unit in the UK of 9,000 patients found that men who take Viagra are at no greater risk of heart problems than the general population."

It is estimated that 20 million men worldwide have taken Viagra.

The research is published in the journal Cell.

[SE Asia Joe]

Did a bit more reading as directed by the info provided by Weelock and found out that these drugs do definitely dramatically increase the risk of going BLIND. Cialis is actually worse (25 times risk increase) than Viagra (18 times increase) as far as going NAION blind is concerned.
Let me see if I can find out the increased risk of death by using these drugs.
SEAJ

Viagra, Cialis & Levitra Information and Warnings

Viagra, Cialis & Levitra are three similar drugs used for the treatment of erectile dysfunction (ED). They work by increasing smooth muscle relaxation and blood vessel dilation, which allows more blood to flow to the penis. These drugs have raised a great deal of controversy because they have been linked to serious and sometimes deadly side effects.
Suffered harm from Viagra? You may have a lawsuit. Click here, for a top rated law firm to evaluate your legal rights.

A study published in 2006 in the British Journal of Ophthalmology was done at the University of Alabama in Birmingham. The study compared men taking Viagra or Cialis (Levitra was not included in the study) who had a history of heart problems with those who did not. The study found that men who had a history of heart attack or high blood pressure 10 times more likely to develop non-arteritic anterior ischemic optic neuropathy (NAION), or stroke of the eye, than men without that history. The study found a smaller increased risk of NAION in men with a history of hypertension. An earlier article in the June 2005 issue of the British Journal of Ophthalmology had reported 7 confirmed cases in which men had developed NAION in the first 3 days of using Viagra.

From 1998 to 2004, the FDA (Food and Drug Administration) received 38 reports of vision loss linked to the use of Viagra and 5 cases with the other two ED drugs. The difference is understandable, since Viagra had been on the market for the full 6 years, while Cialis and Levitra had only been released for a few months at the time of those reports. The FDA required the manufacturers to issue Viagra, Cialis & Levitra warnings. See Drug Warnings: Viagra, Cialis & Levitra Side Effects and Risks for more information.

The consumer advocacy group Public Citizen Health Research Group has criticized the FDA for not taking stronger action and has called for a Viagra, Cialis & Levitra black box warning for NAION. Public Citizen’s own review of research indicates that men taking Viagra are 18 time more likely to develop NAION than other men with similar risk factors, and that men taking Cialis are 25 times more likely to develop NAION. Charles Grassly (R. Iowa) chair of the Senate Finance Committee has requested FDA documents to explain why the FDA had taken so long to notify the public about the risk of NAION.

If you are taking an ED drug and notice changes in your vision, you should stop taking the drug and see your healthcare provider immediately. You should also get immediate help if you notice any problems with your heart or blood pressure.

[SE Asia Joe]

The question is - is Viagra really that safe? And safe for DAILY use?
I know I know, anything done to an excess is no good - but really - if a guy wants a daily pop - is it really all that excessive?

Secondary question - since Ciallis keeps me "ready to go'' for at least a couple days - sometimes even 3 days - is it safer than viagra which requires dosage every 5 or so hours? In that my friend would probably have needed only a dose every few days instead of daily?
SEAJ

Received from Weelock my good buddy by PMS this information on my question

Viagra and Heart attacks

--------------------------------------------------------------------------------

http://injury-law.freeadvice.com/dr...ide-effects.htm


Viagra, Cialis, and Levitra cause drops in systemic blood pressure in many patients. This is caused by a dilation of general blood vessels, as well as the vessels that allow erection of the penis. These drops in blood pressure can bring on cardiac events including:

* Heart attack
* Sudden cardiac death
* Hypertension

Viagra, Cialis, and Levitra have most recently been linked with sudden blindness in one eye, called stroke of the eye, which occurs when the blood supply is cut off to an optic nerve. The patients most at risk for this condition, non-artritic anterior ischemic optic neuropathy (NAION), are men who:

* Have heart disease
* Are over 50 years old
* Have diabetes
* Have high blood pressure
* Have high cholesterol
* Smoke
* Have certain eye problems
Weelock

[Exoticspirit]

You can use 50mg at beginning it is more safe than taking two 25mg,don't forget to drink plenty of water in the morning to flash-out Viagra and minimaized the side effects as stuffy nose.Cheers!

Why would it be safer to take a one time higher dose compared to taking two smaller doses a few hours apart?

[Warsteiner]

Tried both products and indeed works well. But later on did find this one: http://www.libidus-europe.com/ and depending on where you live you can order here: http://www.libidus-pill.com/html/home.html. These are natural products and you will be surprised about the results. I only use the Libidus now and I am super happy with the results.

Have a look at http://www.hc-sc.gc.ca/ahc-asc/media...008_46-eng.php

Warning
2008-46
March 20, 2008
For immediate release

OTTAWA - Health Canada is warning consumers not to use Libidus, an unauthorized product promoted on the web site of the manufacturer for the treatment of erectile dysfunction. The product may pose serious health risks, as it was found to contain the undeclared prescription drug sildenafil, which should only be used under the supervision of a health care professional.

Looks like this contains viagra so not completely 'natural'. This will no doubt be similar to other so-called Viagra competitors (i.e. Palo Alto Aspire 36, etc.) who don't list all of the ingredients in their products. Best to stick to the real thing as at least you know what you are getting.

[Puzzo]

I've taken Viagra only for enhancement for sessions and only at 25 mg with minimal side effects. Only nasal congestion. I'm going to Germany to try out their FKK clubs for the first time later this month. To get the money's worth, most guys will go for average 3-4 girls over several hours during a single club visit. So my question is, if I take say 25 mg at the beginning, can I take another 25 mg say a few hours later in order to help me get through a marathon?

You can use 50mg at beginning it is more safe than taking two 25mg,don't forget to drink plenty of water in the morning to flash-out Viagra and minimaized the side effects as stuffy nose.Cheers!

[Exoticspirit]

I've taken Viagra only for enhancement for sessions and only at 25 mg with minimal side effects. Only nasal congestion. I'm going to Germany to try out their FKK clubs for the first time later this month. To get the money's worth, most guys will go for average 3-4 girls over several hours during a single club visit. So my question is, if I take say 25 mg at the beginning, can I take another 25 mg say a few hours later in order to help me get through a marathon?

[Member #3173]

Can do full sex with spouse but cannot perform outside, ie sometimes transient erection and now none at all even with female stimulation.A doctor friend says it is due to anxiety rather than low testosterone and said if it need be pop in a viagra instead of trying to raise the testo with all the hassle of blood test, rectal examination and so on.

I dont cheong a lot buy it will be nice to feel nice once a while.I am about 62
What do you guys say.Any doctor in the house?

By the way I am on 1/2 tablet a day of Tenoret which is a combination of
atenolol and chlorthalidone i.e. a combo of beta blocker and diuretic

[SE Asia Joe]

It is all too easy these days to attribute a death to an OD, but sometimes, in fact usually, people die because their time is up, be that from a heart attack, stroke, or just old age.

I would honestly think that if anyone could prove any link between V and deaths, that Pfizer would be doing some serious damage limitations. However, I really think that they did their research and are pretty secure in the knowledge that V, for one, is as safe a drug as any drug can be.

Petemcc

Hey Pete:

I believe that you are a male nurse? If so, can you please double check your above statement with some of the doctors you must have daily contact with?

You see, a very good friend of mine, early 50'S, in previous good physical shape (a full medical check up at Bumrungard a year or so ago only reveal a bit elevated Cholesterol level - close to borderline), VERY careful with his diet and fastidious in his hygiene - just had a heart attack and died.

The only thing that I can think of is that he did have a one a day habit - i.e. he would pop one gal per day and to do so, he took Viagra daily. The V was prescribed by his doctor in the States (genuine) and thus no problem with purity etc.

I read your statement about Pfizer and how they must be pretty sure etc - but we all know some of the horror stories with these drug companies and how they would "do things" just to keep sales up.

The question is - is Viagra really that safe? And safe for DAILY use?
I know I know, anything done to an excess is no good - but really - if a guy wants a daily pop - is it really all that excessive?

Secondary question - since Ciallis keeps me "ready to go'' for at least a couple days - sometimes even 3 days - is it safer than viagra which requires dosage every 5 or so hours? In that my friend would probably have needed only a dose every few days instead of daily?

Thanks Pete - and whoever else who could contribute their own knowledge etc on this matter

Ciao
SEAJ

[Gallego]

Tried both products and indeed works well. But later on did find this one: http://www.libidus-europe.com/ and depending on where you live you can order here: http://www.libidus-pill.com/html/home.html. These are natural products and you will be surprised about the results. I only use the Libidus now and I am super happy with the results.

[Duckin Duck]

My first post, I've been reading this forum for years. I fuck some prostitutes from time to time, but don’t feel comfortable writing about it.

When you get to my age, you need help in the Penis department. I'm 62 now and I need those tablets to get an erection.

I can get real Viagra and Cialis on prescription from my doctor buts its too expensive in my country. I had read good and bad reports on this forum about generic Viagra and generic cialis.

I ordered from www.usolinerx.net.. Lots of posts about that company here. Got the stuff after about 2 weeks. Tried the Viagra first, not bad, worked about 70% as well as the real one. 4 days later tried the Cialis and that was better, I reckon that worked just aswell as real Cialis. I got good erections for 2 days after one tablet.

I got the smallest amounts of Viagra and Cialis possible, which amounted to 10 pills of Viagra for $60, and 10 pills of Cialis for $65. At 6 bucks per tablet isn’t bad. I normally take 2 per week, so this lot should do me for about 10 weeks. Next time I'm gonna buy a big amount of just Cialis, like 90 pills for $219 and that should see me right for a year.

Those photos attached, I didn’t take, but the product I got looked very similar.