Stupid shit in Medellin

[Knowledge]

Dear admin, I don't know if there is still a dedicated coronavirus thread. If there isn't may I kindly request you create one and move this thread to it. I only just recently got my friends to stop sending me random lonks and ruminations about this stuff. I am as interested in it as anyone but this is not the place I come to get information on the subject. Thank you very much.

The jury is still out on whether vaccine prevents viral replication or just symptoms. Chances are there are still probably a few asymptomatic but positive covid cases amongst those who receive the vaccine. But I think it's safe to say that vaccinated individuals, if asymptomatic, will probably have a lower viral load and will shed less virus.

And yes, they've said that a single dose would be sufficient but who knows.

[Rextor]

I am so dismayed by reading this. Considering the low probability that after infection one falls so severely sick to die, the real big reason to be concerned is not what pain I will personally suffer, but the chain of infections that I could start and feed.

The jury is still out on whether vaccine prevents viral replication or just symptoms. Chances are there are still probably a few asymptomatic but positive covid cases amongst those who receive the vaccine. But I think it's safe to say that vaccinated individuals, if asymptomatic, will probably have a lower viral load and will shed less virus.

And yes, they've said that a single dose would be sufficient but who knows.

[Black Page]

I'm basing my numbers off of the AstraZeneca vac which showed 60% at a double dose of adenovirus.

The surprising thing is that they found that 1+1 doses (28 days apart) achieved some 60% protection, but 0. 5+1 doses (half dose then one full dose 28 days after) achieved 90%.

They are still reflecting on possible explanations, but however they will repeat the 0. 5+1 pattern on more volunteers to achieve better confidence of results.

Vaccines are not a simple matter. Usually several years are needed to complete the experiments, now they try to validate results in less than one.

[Black Page]

Johnson and Johnson. I'm expecting around 60-70% efficacy, but I'm already young and healthy so not too concerned.

I am so dismayed by reading this. Considering the low probability that after infection one falls so severely sick to die, the real big reason to be concerned is not what pain I will personally suffer, but the chain of infections that I could start and feed.

Imagine you get infected, but you don't have symptoms and / or you don't care of others around you. You pass the virus to some people (it does not matter how many, even just 1, 2 o 3). Some of them pass the virus to some others. An exponential tree starts to grow. After some weeks or months, the tree has reached tens, then hundreds persons. The probability that at least some of those hit by the tree dies is close to 1. I could not live with the regret of awareness that I am the original source of all that.

There would not be so much to be worried, if the problem of COVID was just the <1% of casualties among infected. The problem is its destructive massive spreading, with at least 50% asymptomatic, which has the power to produce a mass carnage and saturation of hospitals in few months if uncontrolled.

[Black Page]

P.S. - I took an antibody test here in Colombia and it came back negative. Hence why I'm only 90% sure. But a fever couldn't be a figment of my placebo-induced imagination. I think more likely the blood tests was a false negative. Will verify when I'm back in the states.

I read from a 16 Nov news:

"Johnson & Johnson is confident that it has a one-dose knockout vaccine that can protect against COVID-19, but it's now starting a late-stage two-dose test just in case.

The Big Pharma's vaccine, Ad26. COV2. S (now also known as JNJ-78436735), is currently in a major 60,000-subject phase 3 known as ENSEMBLE assessing whether it can stop COVID-19 infections with a single shot.

Early data have already shown it can produce an immune response at one dose, but now it wants to test out a two-dose schedule. ".

[JjBee62]

[URL]https://www.nationalreview.com/corner/elderly-woman-euthanized-to-avoid-anguish-of-lockdown-loneliness/?utm_source=recirc-desktop&utm_medium=article&utm_campaign=right-rail&utm_content=top-stories&utm_term=second[/URL.

Damn. That makes me feel old. I remember when The National Review was a respectable publication. If that story is representative of what it's become, at least now I know what became of the hacks who formerly published "The Weekly World News."

Please tell me you only read it to laugh at the 5th grade writing style.

[MarquisdeSade1]

I appreciate your perspective on this, and I happen to be over 65, hence this may help to explain my perspective, and what my fears were, and hence my report. It is refreshing to see a post from an administrator on this board, and I agree totally with your analogy.

https://www.nationalreview.com/corne...tm_term=second

[Rextor]

So you were enrolled in the J & J trial, and I'm assuming you know you didn't get the placebo, and if so, how do you know you. Did J & J inform you of this, and if not, did you have some minor reactions to the shot like temperature, etc. In reading your original post it almost sounded as though you went and got vaccinated somewhere, almost like going to a pharmacy in the USA for a flu shot. Lot's and lot's of Mongers I believe are sitting on the sidelines waiting to get vaccinated before resuming their hobby.

Yeah its the JnJ vaccine trial. I'm like 90% sure I didn't get the placebo. I was exhausted enough to fall asleep at 9 pm the day I got the vaccine, then woke up in the middle of the night shivering while my apartment was 80 degrees Fahrenheit. Fever of 102, headache, nausea, tender arm where they injected me. Sucked feeling shitty but felt great to know that I would have some degree of protection against this damn virus. And that I would be able to travel stress free months before everyone else could. 100% worth it.

P.S. - I took an antibody test here in Colombia and it came back negative. Hence why I'm only 90% sure. But a fever couldn't be a figment of my placebo-induced imagination. I think more likely the blood tests was a false negative. Will verify when I'm back in the states.

[Surfer500]

I recd the University of Chicago / Moderna vaccine 2 x including side effects, I feel like Superman, where are all the putas?

Hit El Centro and open shop. Book a hotel with an unlimited visitors policy, perhaps Premier Plaza with a slight upcharge. Post a banner from the balcony that says you'll pay 25K a pop. There will be a line of at least 100 girls or more lined up within 15 minutes as word will spread fast. Than you have the task of screening them all, probably 90% of them and ejecting them based solely on appearance, and then the interview process of what your expectations are for that 25K of the ones that make the first cut. Maybe hire an assistant to help you prioritize, and schedule those who will agree to your requests, but at a later date when you become leche depleted and can't be knocking them out every hour on the hour.

[Surfer500]

Different vector and dosage. The pfizer / moderna vacs have two injections and are mRna / nanoparticle based. JJ is adenovirus vector with just a single dose. I'm basing my numbers off of the AstraZeneca vac which showed 60% at a double dose of adenovirus. I would think that the JJ would be similar to that, but looking at the Phase 1/2 results of both vacs showed that JJ had a higher neutralizing antibody level. So I think the weakness of the single dose is balanced against the higher antibody count / immunogenicity to average around similar to what the AstraZeneca vac showed. But I'm just making this shit up so who knows.

So you were enrolled in the J & J trial, and I'm assuming you know you didn't get the placebo, and if so, how do you know you. Did J & J inform you of this, and if not, did you have some minor reactions to the shot like temperature, etc. In reading your original post it almost sounded as though you went and got vaccinated somewhere, almost like going to a pharmacy in the USA for a flu shot. Lot's and lot's of Mongers I believe are sitting on the sidelines waiting to get vaccinated before resuming their hobby.

[Rextor]

On what basis? I understand that the J&J attacks the spike protein in just same way as most other recent vaccines. I believe the efficacy will be the same.

Different vector and dosage. The pfizer / moderna vacs have two injections and are mRna / nanoparticle based. JJ is adenovirus vector with just a single dose. I'm basing my numbers off of the AstraZeneca vac which showed 60% at a double dose of adenovirus. I would think that the JJ would be similar to that, but looking at the Phase 1/2 results of both vacs showed that JJ had a higher neutralizing antibody level. So I think the weakness of the single dose is balanced against the higher antibody count / immunogenicity to average around similar to what the AstraZeneca vac showed. But I'm just making this shit up so who knows.

[MarquisdeSade1]

Already vaccinated? Were you part of the Pfizer trial, if not, where did you get vaccinated?

I recd the University of Chicago / Moderna vaccine 2 x including side effects, I feel like Superman, where are all the putas?

[John Clayton]

I'm expecting around 60-70% efficacy...

On what basis? I understand that the J&J attacks the spike protein in just same way as most other recent vaccines. I believe the efficacy will be the same.

[Rextor]

Already vaccinated? Were you part of the Pfizer trial, if not, where did you get vaccinated?

Johnson and Johnson. I'm expecting around 60-70% efficacy, but I'm already young and healthy so not too concerned.

[Surfer500]

Appreciate the concern man, but I've already been vaccinated so I'm good to go. Much more scared of catching herpes or a knife in the ribs at this point haha.

Already vaccinated? Were you part of the Pfizer trial, if not, where did you get vaccinated?