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05-01-20 00:06 #17347
Posts: 657Chloroquine is a potent inhibitor of SARS coronavirus infection and spread.
Background: Severe acute respiratory syndrome (SARS) is caused by a newly discovered coronavirus (SARS-CoV). No effective prophylactic or post-exposure therapy is currently available.
Results: We report, however, that chloroquine has strong antiviral effects on SARS-CoV infection of primate cells. These inhibitory effects are observed when the cells are treated with the drug either before or after exposure to the virus, suggesting both prophylactic and therapeutic advantage. In addition to the well-known functions of chloroquine such as elevations of endosomal pH, the drug appears to interfere with terminal glycosylation of the cellular receptor, angiotensin-converting enzyme 2. This may negatively influence the virus-receptor binding and abrogate the infection, with further ramifications by the elevation of vesicular pH, resulting in the inhibition of infection and spread of SARS CoV at clinically admissible concentrations.
Conclusion: Chloroquine is effective in preventing the spread of SARS CoV in cell culture. Favorable inhibition of virus spread was observed when the cells were either treated with chloroquine prior to or after SARS CoV infection. In addition, the indirect immunofluorescence assay described herein represents a simple and rapid method for screening SARS-CoV antiviral compounds.
https://www.ncbi.nlm.nih.gov/pubmed/16115318
Nutshell: Chloroquine has been known since 2005 to be "a potent inhibitor of Sars Coronavirus. . . " NIH: Director About NIAID Director, Anthony Fauci, M. The.
https://www.niaid.nih.gov/about/anthony-s-fauci-md-bio
Originally Posted by WombatEd2 [View Original Post]
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04-30-20 20:43 #17346
Posts: 536Some Blogger On the InterNutz Says.
Originally Posted by Travv [View Original Post]
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04-30-20 10:40 #17345
Posts: 106The Border
Contrary to my previous report, crossing north at San Ysidro no longer has the fast window at midnight. Dunno what happened, but just sat through a 2 hour wait at approximately the same time frame where a month ago took less than 3 minutes. BWT websites, both app and Chrome showed an increase where they're normally conservative estimates. YMMV. A real crapshoot.
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04-30-20 07:43 #17344
Posts: 657Media lied, people died: Italian study finds incredible Prophylaxis Results for HCQ
Media lied, people died: Italian study finds incredible. Prophylaxis Results for Patients on Hydroxychloroquine.
And now a new study from hard-hit Italy found that those Italians on hydroxychloroquine for Lupus or Rheumatoid Arthritis did not come down with the coronavirus. Only 20 patients (out of 65000) tested positive for COVID-19. No ICU, and no one died!
Via Dr. James Todara, MD.
https://www.thegatewaypundit.com/202...sharingbuttons
I've been taking HCQ for about 5 weeks per the Indian Ministry of Health Council reco for doctors treating COVID patients plus zinc daily. So I'm taking trips to Tijuana without worries about getting the China fever. Have visited farmacias in Tijuana to buy more HCQ and now it is much more difficult, likely due to hoarding by pharmacists and doctors.
Originally Posted by WombatEd2 [View Original Post]
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04-30-20 07:05 #17343
Posts: 536Originally Posted by TjBrazil [View Original Post]
So if the SA gal is infected, so are you.
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04-30-20 06:37 #17342
Posts: 553Originally Posted by Dogers69 [View Original Post]
How in the world did you come to the conclusion that "it just sounded like they liked Mexico"? Huh? What? We're not talking about white sandy beaches of Cancun or Cabo San Lucas. Ciudad Juarez is an ugly ass, mega dangerous, semi war zone, hell hole. This guy is a good looking guy with money. He was only in Juarez to be with her, because that's her home, and they were quarantining together.
And yes I'm thinking that there's a good chance that she has a "prior boyfriend" with big dinero who paid for her fancy vacations. And whether he was a narco or not, it's probably not difficult for a jealous local guy with money to arrange a hit on some outsider who's in town shacked up with his gorgeous ex novia.
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04-30-20 05:42 #17341
Posts: 99Originally Posted by Fryer45 [View Original Post]
Last Friday I was able to enter Mexico at San Luis Rio Colorado, but the next morning when I was coming back to the US, CBP held me for nearly 2 hours and gave me a ration of shit before letting me go. Honestly, I attribute this to them having a lot of spare time since the port is so dead. I plan to visit Los Algodones again this Saturday for an overnight with my regular girl, so I'll update this thread when it happens.
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04-30-20 05:19 #17340
Posts: 994Trump's Social Distance Order expires today. Mask not a requirement
Governor Newsom Stay at Home Order in place till May 15 and today closing all beach from MEX to Oregon border. Arizona Stay at Home Order in effect? Not enough known about CBP action now. It is easy to loose SENTRI and GLOBAL privilege.
Originally Posted by Fryer45 [View Original Post]
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04-30-20 05:18 #17339
Posts: 1478Originally Posted by Jinxx [View Original Post]
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04-30-20 02:06 #17338
Posts: 244Answers, maybe.
Originally Posted by Sound7 [View Original Post]
Fryer45.
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04-30-20 01:42 #17337
Posts: 1947Originally Posted by DickusMaximus [View Original Post]
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04-29-20 23:15 #17336
Posts: 155Originally Posted by Sound7 [View Original Post]
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04-29-20 21:03 #17335
Posts: 3198Originally Posted by Sound7 [View Original Post]
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04-29-20 19:03 #17334
Posts: 994Governor Newsom's Phase. Stay at Home Order. April 28.
Phase I is in place for California. Border crossing is impacted by this Stay at Home Order, Phase I.
April 4, CBP staff reinforced the California Stay in Order in a confused way. California Phase II is projected for the coming weeks and not months.
What is CBP doing currently to prevent visit to Tijuana?
Rx was a No No on April 4. CBP.
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04-28-20 08:59 #17333
Posts: 279Originally Posted by Jinxx [View Original Post]