Rants and WTF are you talking about and Coronavirus!

[QUOTE=Tuber19;2500618]Merkel: Nurses and doctors vaccinate first against coronavirus.

https://rejerusalem.com/287436/merkel-nurses-and-doctors-vaccinate-first-against-coronavirus/

((The federal government hopes that the first vaccines will be approved very soon. "So of course there will not be enough vaccines available", said the Chancellor and stressed: "No one will be forced to be vaccinated, it is a voluntary decision".

Preparations for a vaccination campaign are underway. Federal states have planned their own vaccination centers. It remains to be seen how much vaccine will be available and how long that vaccine will be immunized. The main task is to make the population as a whole immune to the virus. If 60 to 70 percent of the population are immune by vaccination or a disease from which they have suffered the virus is "more or less defeated," Merkel said. " *Then we can also lift all the restrictions* " she said.)).

Lets hope this is done ASAP.[/QUOTE]Nobody knows if the vaccine is efficient, it seems that the covid 19 is able to mute very fast so the vaccine like for the normal flue is far less efficient.

[QUOTE=ExpatLover;2500641]Nobody knows if the vaccine is efficient, it seems that the covid 19 is able to mute very fast so the vaccine like for the normal flue is far less efficient.[/QUOTE]Yes most viruses mutate very fast in comparison to multicellular organisms. But that fact may or may not be relevant. Most viruses and unicellular organisms mutate all the time. Even human somatic cells have a degree of consistent "mutation. " They can happen by exogenous causes (radiation) but so much more often during the replication processes. The reason that it is often not of any relevance is that most mutations have zero consequence. For mutations to be an issue in vaccine recognition, first the mutation must be expressed. And even if expressed, it has to be at an antigen site in which antibodies bind. Then the change of binding site must be significant enough so that antibodies no longer recognize it. That itself is not a black or white scenario. Usually it's that the binding just has various degrees of lowering affinity. It takes many things to go right for a microbial mutation to be so drastic as to make a vaccine completely ineffective. And in reality it's not that there's a purposeful mutation, but rather just a case of genetic selection in which a specific genetic variation allows that particular "strain" to spread unchecked. Furthermore, the genetic variation must be both specific enough to be located at the site of antigen recognition but not alter the pathogenicity of the virus. That is why vaccines are developed to recognize antigens that are associated with pathogenicity. Very few exceptions exists due to their nature such retroviruses like HIV that become latent and "hides" while also exhausting immune cell resources. Or influenza because it mutates extremely fast. In comparison to the 24 HR and 6 HR life cycles of HIV and Influenza, coronaviruses sit for days. Days in comparison to hours.

Point in short is that the scary idea of mutating viruses is just that, scarier than it sounds. Possible to render a vaccine useless, but more often than not, they are insignificant.

[QUOTE=ExpatLover;2500641]Nobody knows if the vaccine is efficient, it seems that the covid 19 is able to mute very fast so the vaccine like for the normal flue is far less efficient.[/QUOTE]It's meant to boost population confidence. Nurse, doctors, old folks, and possibly students first would be my best guess. It will be amazing if the nurses / doctors who are busting their asses to save folks fall ill themselves.

[QUOTE=HammerTime96;2500625]Of course, anyone with 2 braincells could have figured out that a vaccination against a permanently mutating Corona virus is not going to work, but the lies and scaremongering of geriatric people afraid of a flu and their own shadow seem to have the loudest voice here on ISG.

For all the fools still hoping for a "vaccine:

[URL]https://www.cnbc.com/2020/11/06/who-looking-at-how-a-covid-mutation-among-minks-may-impact-a-vaccine.html[/URL]

"The detection of the mutated virus among minks has raised questions about the effectiveness of a future Covid-19 vaccine."

[URL]https://www.newscientist.com/article/2259178-is-a-dangerous-new-coronavirus-strain-circulating-in-farmed-mink/[/URL]

"The Danish prime minister described the mutated virus as "a serious risk to public health and to the development of a vaccine."

[URL]https://www.bbc.com/news/science-environment-54842643[/URL]

"Every time the virus spreads between animals it changes, and if it changes too much from the one that is circulating within humans at the moment, that might mean that any vaccine or treatment that will be produced soon might not work as well as it should do," she explained."[/QUOTE]The jury is still very much out on this one, though Hammer Hammer is jumping to conclusions, saying what the scientists aren't saying, grasping for any kind of face saving on a monger board. Below is a quote from the CNBC article you linked, and we should take this to heart. Hammer BTW, how did you like the election results? Take heart though as there will still be plenty of conspiracy theories for you to chase down, more than enough to keep you busy. And that clown / loser Trump will still be around to help you along.

"We have to look at that viral evolution, we have to create the biosecurity around farms like that so that there is not that contact back with human populations. And we have to address all of those issues. But, right now, the evidence that we have does not suggest that this variant is in any way different in the way it behaves," he added.

Ryan said the WHO would have to evaluate whether the mutation of the virus among the mink population is different in terms of its clinical severity or whether there is any implication for diagnostics or vaccines. "But we are a long, long way away from making any determination of that kind," he said.

Dr. Soumya Swaminathan, the World Health Organization's chief scientist, said it would be unwise to jump to any conclusions following reports of the mutated virus found among mink farms in Denmark.

"I think that we need to wait and see what the implications are, but I don't think we should come to any conclusions about whether this particular mutation is going to impact vaccine efficacy or not," Swaminathan said.

"We don't have any evidence at the moment that it would. But we will update you as we get more information."

Look at the data: [URL]https://ourworldindata.org/coronavirus-data-explorer?zoomToSelection=true&time=earliest..latest&country=LUX~FRA~DEU~NLD~SWE~ITA~ESP~GBR~USA~RUS&region=World&deathsMetric=true&interval=total&perCapita=true&smoothing=0&pickerMetric=location&pickerSort=asc[/URL].

Sweden's "death per millions" has flat-lined since July, but in the rest of Europe with their stupid lockdowns and face diaper 'strategy,' not so much.

[QUOTE=Paulie97;2500694]The jury is still very much out on this one, though Hammer Hammer is jumping to conclusions....[/QUOTE]You obviously didn't see the question mark in the title of my post.

Ask yourself this: "why hasn't anybody made a good vaccine yet for the normal cold and the seasonal flu during the last 20-30-40 years?

So why would anybody now be able to quickly make a vaccine in 1 year time, against a constantly mutating virus?

As the saying goes, "hope dies last." Keep on hoping for the impossible, and keep on ignoring the natural solution that has worked for thousands of years that is right in front of your nose: herd immunity!

Look at the Swedish numbers: flat-lining since July, while the rest of Europe keeps on slowly rising. The irony: the countries where the rising is steepest, are the countries with the most strict and most absurd rules (Spain, France, UK), and the only country where the curve has flat-lined is Sweden which has the least amount of madness and the least amount of crazy rules about masks and social distancing:

[URL]https://ourworldindata.org/coronavirus-data-explorer?zoomToSelection=true&time=earliest..latest&country=LUX~FRA~DEU~NLD~SWE~ITA~ESP~GBR~USA~RUS&region=World&deathsMetric=true&interval=total&perCapita=true&smoothing=0&pickerMetric=location&pickerSort=asc[/URL]

Told you. Coronavirus will be cured in November if Trump loses.

[QUOTE=HammerTime96;2500796]You obviously didn't see the question mark in the title of my post.

Ask yourself this: "why hasn't anybody made a good vaccine yet for the normal cold and the seasonal flu during the last 20-30-40 years?

So why would anybody now be able to quickly make a vaccine in 1 year time, against a constantly mutating virus?.[/QUOTE]For other people who have to answer this question, you can file this retort away:

-No vaccine for common cold because the "common cold" is not caused by one specific virus. Hundreds of different viruses may cause the symptoms described as the "common cold."

-Influenza vaccines obviously exist and have decent efficacy. Annual requirements are due to the fact that it replicates extremely fast compared to most other viruses. The shorter the life cycle, the more mutations, increasing the possibility of the mutation providing resistance to vaccines. For comparison, coronavirus replication is, at minimum, twice as long, with mutation rates possibly up to a whole degree of magnitude longer because it has an even longer latent period.

[QUOTE=Gino02;2500886]Told you. Coronavirus will be cured in November if Trump loses.[/QUOTE]It has been cured? Really?

A bit sad to see this sort of whiny desperation from Trump supporters.

The vaccine is not any more ready today than it was yesterday but the news have been released today. In any case, Trump ignored Fauci and others and put all his eggs in one basket when they kept saying it would not be ready by Nov 3. But this is a piece of good news and hopefully we can get some control on this and be able to return to pre covid movement levels in a few months. I am sure you welcome the opportunity to travel and visit your favorite fuck clubs in Europe and so do I.

Let's face it. Trump has been a major fuck up. I mean, he can't even do the legal contests properly. Putting Rudy in charge is not the best strategy. In 2000, Bush had hundreds of lawyers ready and waiting, paid and money raised, to focus on one state. Trump is making a lot of empty noise and playing golf and throwing shit in every direction (kinda like a fuckterd "doctor" on this site).

The guy is fucking incompetent. The only thing he has been any good is somehow convincing 70 mil voters he is their one and only savior regardless of how much he screws up. He had good instincts on China trade and some elements of popularism in US economics given the widening income / wealth disparities but he is too much of a scatterbrain to actually execute on anything. I am not thrilled Biden is coming in, but AOC / Bernie will not dominate given the senate situation and it is actually an OK thing to have a lot of logjam in DC. When pols have too much power, they fuck it up regardless of the party affiliation. It is good to have a deadlocked bunch of guys on both sides.

[QUOTE=HammerTime96;2500796]You obviously didn't see the question mark in the title of my post.

Ask yourself this: "why hasn't anybody made a good vaccine yet for the normal cold and the seasonal flu during the last 20-30-40 years?[/QUOTE]They make flu vaccine every year and it is effective. Cold is not severe enough to warrant the development of a vaccine.

Something for the conspiracy theorists that news that the vaccine is almost ready is published on the first weekday after consensus was that Biden won.

[QUOTE=Ararat;2500910]Something for the conspiracy theorists that news that the vaccine is almost ready is published on the first weekday after consensus was that Biden won.[/QUOTE]Yup. When there's smoke.

Part of the rhetorical question was irrelevant as Covid-19 isn't "the flu," thus it deserved to be ignored. And of course there are flu vaccines.

Unlike Covid-19 the common cold is caused by hundreds of different viruses, not just one. It's been a lower priority for vaccine development as it's a relatively mild illness, though one is still possible for the future as science progresses. To use this information plus the flu and the mink story, which has been shown to prove nothing as yet, to leap to the conclusion that vaccine development is a waste of time, that reputable scientists the world over all have it wrong or are perpetuating a hoax, show you as possessing two brain cells maximum. Such wasn't worth a response though I was bored this afternoon.

You also contradict yourself lifting up Sweden, for if an effective vaccine is impossible then so is herd immunity. Not to mention that Sweden is a demonstrated failure, having needlessly sacrificed the lives of 5000+ of it's citizens, 11 times the per capita death rate of it's neighbor Norway, chasing her immunity.

[URL]https://time.com/5899432/sweden-coronovirus-disaster/[/URL]

Regarding Covid mutations, here's more info that echos the article you posted, the one you thought supported your conclusions but as demonstrated, did not. Listen to the scientists people, not kooky posts in social media and conspiracy theory peddlers in monger forums.

"One variable shaping efficacy is how quickly the virus mutates. A faster rate of mutation would increase the likelihood that the vaccine would not generate an effective immune response to the virus. SARS-CoV-2, the virus behind Covid-19, is a single-stranded RNA virus. Such viruses are notorious for high mutation rates, but those mutations don't necessarily occur in a way that would weaken protection from a vaccine.

"Measles is also a single-stranded RNA virus. It mutates a little but it doesn't mutate away from the vaccine," said Paul Offit, director of the Vaccine Education Center at the Children's Hospital of Philadelphia. "I think that you're not going to need to do what you do with influenza where you have to get a yearly vaccine. Influenza is a moving target. That's not going to be this virus. "

[URL]https://www.vox.com/2020/6/3/21258841/coronavirus-vaccine-covid-19-testing-usa-china-moderna[/URL]

Also on the vaccine front, good news! That plus Trump's lose and I'm loving the looks of my stock portfolio.

[URL]https://www.usatoday.com/story/money/markets/2020/11/09/dow-pfizer-vaccine-biden-election-results-stock-market-record/6219095002/[/URL]

[QUOTE=HammerTime96;2500796]You obviously didn't see the question mark in the title of my post.

Ask yourself this: "why hasn't anybody made a good vaccine yet for the normal cold and the seasonal flu during the last 20-30-40 years?

So why would anybody now be able to quickly make a vaccine in 1 year time, against a constantly mutating virus?

As the saying goes, "hope dies last." Keep on hoping for the impossible, and keep on ignoring the natural solution that has worked for thousands of years that is right in front of your nose: herd immunity![/QUOTE]

[QUOTE=Ararat;2500910]Something for the conspiracy theorists that news that the vaccine is almost ready is published on the first weekday after consensus was that Biden won.[/QUOTE]Agreed. Check this video out: [URL]https://youtu.be/ZG2m8kb-P0Q[/URL].

[QUOTE=Ararat;2500910]Something for the conspiracy theorists that news that the vaccine is almost ready is published on the first weekday after consensus was that Biden won.[/QUOTE]What goes around comes around. Trump deserves to be lied to, just as he did his entire "presidency". If Pfizer and BioNTech deliberately withheld the good news until after the election, I applaud them. Hope we are on the path getting rid of both T and covid. FKK 2021, we are ready!