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Hematology 201 - sophomore year.
T cell binding to platelets do not cause platelets to form blood clots, no matter where they bind. By definition, platelets aggregates are not even actual blood clots. Instead, they promote the formation of thrombin clots, actual blood clots.
Thrombotic thrombocytopenia on the other hand, is a condition in which platelet levels become depleted but immune complexes formed in part by platelet granules and various molecules are bound by antibodies that recruit thrombin, leading to thrombosis, especially in arteries. What we see in CSVT are venous blood clots.
T cells do not tell tell platelets what to do, rather platelets can activate T cells to perform various tasks of the immune system.
I searched Up-to-Date, the premiere source of established medical knowledge in the United States, and no where does the literature have any mention of T-cell induced thrombosis in relation to platelets. In every direct instance, T cells play a role in the degradation of blood clots, not their formation.
Autoimmune thrombotic thrombocytopenia however can result in platelets initiating a sequence of events that leads to blood clots but they are facilitated by antibodies which are produced by B_cells. The function of T cells in this instance, is at best, to facilitate some secondary cell-cell communication. I'm too far from undergrad to remember those details. But for that to occur, both B_cells and T cells must develop an autoimmune disorder. Odd thing is that these blood clots are not implicated in the mRNA vaccines. Another conspiracy myth.
As such, if someone was to say that aberrant autoimmune B_cell activation leads to immune complex formation with platelet granules leading to thrombosis, they would be correct. Insisting on T-cells binding to sites on platelets causing clot formation, well that shows a lack of understanding likely due to a lack of fundamental, life-science foundation. Throw in some unbelievably mis-found arrogance too.
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HammerTime: Did you read this?
80% of the people in Sicily are turning down the vaccine from AZ!
[URL]https://www.businessinsider.com/sicily-80-percent-turn-down-astrazeneca-vaccine-hesitancy-2021-4[/URL]
1000 - 0.
To us anti-vaxxers and the Sicilian mafia against the wannabe know-nothing corrupt death spawns on this forum!
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[QUOTE=PahllusMaximus;2551005]Works better than garlic.[/QUOTE]Actually, garlic extract is quite good for your blood. Allcin has some good properties. Add it with onion to your diet and you are good!
Take it from the real doctor here on the forum! No need for scam-ridden mafia products at the pharmacy.
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[QUOTE=Mursenary;2550965]As for CSVT (cerebral blood clots), we've seen that the pauses in AZ and now JJ vaccines occurred when the incidence was well below the background incidence.[/QUOTE]LOL!
In 2.7% of the test subjects who received the AZ vaccine, the amount of T-cells in their blood broke the chart. They couldn't even measure the amount!
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[QUOTE=PahllusMaximus;2551005]You would be amazed how many people believe in UFOs, made up gods and various delusions. Most lack critical thinking too. Much of the stuff about vaccines is straight up mental. There is a market for the crazy, mysticism and etc.[/QUOTE]I don't have as much disdain for the American people as you, but fair.
But since we are all entitled to one belief or two without proof, UFO's are definitely possible.
Well, at least aliens are. Human sized spaceships may not be needed for interstellar travel.
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[QUOTE=Clodius1;2551014]J&J is a disaster, but USA will be okay, defense in depth. We have enough oversupply of Pfizer and Moderna to screw up everyone's DNA here, no problem. Yes, I'm still glad that I got the J&J, older tech is better than new.[/QUOTE]I understand your apprehension. Fair enough. Old tech vaccines will be very useful in ending this foolishness.
But once you shed the pop culture influences, the mRNA vaccines are superior in every way except for the logistics of delivery (cold storage, 2-dose schedule).
They are deliberate and specific (encodes for specific viral proteins, no more, no less). They are delivered in innate lipid particles as opposed to immunogenic vectors required with traditional vaccines. That means they infuse to cells and deliver the "package" without the need for viral / bacterial vectors that illicit non-specific immunogenic responses. They are easily altered for future adjustments as antigenicity shifts in the virus.
The comparisons of the two technologies is like comparing MP3's versus tape cassettes. Microsoft Word versus Typewriters.
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[QUOTE=Clodius1;2551014]J&J is a disaster[/QUOTE]That's what I said! And they always have been!
Though the amateurs in here have advocated otherwise.
Or wait? Are they actually changing their minds too now?
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Sigh
Levity aside.
I'm only a year 1 university biochemistry dropout and am pretty ignorant, but I know the difference between subunits, attenuated, adenovirus, and deactivated and proteins and ligands and most of the cellular components. Cells in humans are vastly different in what they do. I'm smart enough to know much smarter people than me are on this little problem. It's not in some dark room with cigars by some elite or CIA / UFO / government cover up / Bill Gates blah blah conspiracy. That's not to say they are not exploiting it economically, but that's another topic.
Our DNA is morphing and changing all the time, slowly, radiation, virii and the proteins are all replicating, dying or mutating, cancer being the penalty for multi-cellular. We have about 60-100 trillion cells. Some will change for any number of reasons. This is how evolution works. It's a big squishy mess and not particularly well designed in some ways, and brilliant in other ways. In fact, based on left-hand sugars found in meteors, there is a fairly high chance earth got seeded by bombardment a long time ago. Ladies milking cows (not cocks) did not get smallpox, and were unwittingly getting a natural vaccine. So crapping on about vaccine fucking up our DNA is pretty way out there. It would take enormous effort to get collusion of thousands of labs in different countries testing and cross checking. There is probably nearly a people with PhDs working on this. That's why conspiracies are mostly bogus. Incompetence is far more likely. Chances are you have HPV from the many girls we have had. It too changes protein expression that DNA / RNA folds. There is noting bad about virii per se. There are so many they are probably essential.
What has changed is a giant megaphone and social media that enables everyone to be an expert. If we went back to the 1950's with polio, and gave everyone a smart phone, we would be as fucked up as we are today. The lack of trust in politicians and institutions fans the flames, and selling BS is profitable. Keeps the population fighting over bullshit rather a cool look at income to asset price growth curve, falling income and the sucking squid of Wall Street. Vaccines, trans-gender soy beans, gun rights and other BS is the distraction trick.
All too hard. I need a BJ. And for Thailand and FKKs to open. There are clever guys on this forum,but some are dropkicks. The DNA altering conspiracy is absurd.
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[QUOTE=Mursenary;2550945]To clarify, are you just stating your criticism of the process? (Not writing to you in French and depriving you of a phone call).
Or are you saying that you were innocent altogether, not ever speeding on Swiss highways and have never been "flashed" by a traffic control device?
The latter would not excuse the first offense by the Swiss authorities but would help your audience here formulate a better understanding of your gripe.[/QUOTE]How much can he be believed anything he is claiming? Initially he claimed he was never speeding, then he changed it to never caught they can't prove it was him, latest is well he was on a highway so who cares about speed limit signs, plus it is so stressful for him to drive under 120, then it turns out he got multiple fines. If he got the letters only in German, and that is a big if, anybody could read there that it was from police in Switzerland, it would have the speed in km / h, date and location of infraction and an amount to be paid. Would it be really that difficult to understand what it is about? It wasn't written in Cyrillic or Hanzi or Kanji characters. You got caught speeding, tough luck buttercup, actions have consequences, be a man, pay up, be more careful next time.
I am sure it is possible to antagonize police officers, just be a dick to them. It's high up on the list of stupid things you can do when in a foreign country. If you really try to annoy them, they can find a way to make things interesting. Comparing such a situation with human rights violations in China or Russia is just ridiculous and an insult to people who really are affected by them.
Never mind the other delusions, 50+ guy who does less than 1000 km per year cycling (this is what pros do in 5 race days), but claiming he is fitter than a still active multiple world champion, the monger who gives most prostitutes their first ever orgasm in life, etc, etc.
How credible is anything coming from the same person?
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[QUOTE=Mursenary;2550945]To clarify, are you just stating your criticism of the process? (Not writing to you in French and depriving you of a phone call).
Or are you saying that you were innocent altogether, not ever speeding on Swiss highways and have never been "flashed" by a traffic control device?
The latter would not excuse the first offense by the Swiss authorities but would help your audience here formulate a better understanding of your gripe.[/QUOTE]Only flashes on cars, but driver was never arrested overspeeding in Switzerland, only controls on borders or elsewhere, when I was arrested in Germany and I paid, so if You are able to understand, just 0 proof about the driver in Switzerland. Then, letters written in German when law is to write me in French, to make sure I understand the charge. Then abusive justice charge and treating me like a criminal to put pressure on me, when 0 proof despite they put messe in my car, so I m innocent according to law, but then behaving like a criminal, as they treated me. My very easy way for thinking and like with girls, my principles are more important than grocery and arithmetic. But as I previously wrote, as I doubt to have my 2 followers climbing with me on this Summer, maybe only their carbon light bicycles climbing alone and less heavy, when I m sure my french brand and me will be able to climb more than Sagan will climb on this year, with about 30 highest ranked, more than Giro, tour de France and Vuelta all together for highest ranked climbings, for great Summer I want to make, just my subjective way of thinking and like in brothels I don t care about jealous obsessed followers, Kate told me about when she was bullshit by some, who don t know the meaning of addiction. Maybe You should explain this disease to your friends who would run to brothels if they could.
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[QUOTE=Gino02;2550991]France suspends all Brazil flights over Covid-19 variant fears.
[URL]https://www.france24.com/en/europe/20210413-france-suspends-all-brazil-flights-over-covid-19-variant-fears[/URL]
Is this a racist action?[/QUOTE]2020 wants its joke back.
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[QUOTE=Mursenary;2551135]2020 wants its joke back.[/QUOTE]He crushed you as usual.
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[QUOTE=Sirioja;2551088]Only flashes on cars, but driver was never arrested overspeeding in Switzerland, only controls on borders or elsewhere, when I was arrested in Germany and I paid, so if You are able to understand, just 0 proof about the driver in Switzerland. Then, letters written in German when law is to write me in French, to make sure I understand the charge. Then abusive justice charge and treating me like a criminal to put pressure on me, when 0 proof despite they put messe in my car, so I m innocent according to law, but then behaving like a criminal, as they treated me. My very easy way for thinking and like with girls, my principles are more important than grocery and arithmetic. But as I previously wrote, as I doubt to have my 2 followers climbing with me on this Summer, maybe only their carbon light bicycles climbing alone and less heavy, when I m sure my french brand and me will be able to climb more than Sagan will climb on this year, with about 30 highest ranked, more than Giro, tour de France and Vuelta all together for highest ranked climbings, for great Summer I want to make, just my subjective way of thinking and like in brothels I don t care about jealous obsessed followers, Kate told me about when she was bullshit by some, who don t know the meaning of addiction. Maybe You should explain this disease to your friends who would run to brothels if they could.[/QUOTE]You just have no moral and no honor. You are overspeeding so many times and you don't have the honesty to admit it, you just try to escape your responsibility, you are saying you are a accomplished sportsmen are those the rules you are defending, like cheating, lying, no respecting the laws.
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[QUOTE=Clodius1;2551014]J&J is a disaster, but USA will be okay, defense in depth. We have enough oversupply of Pfizer and Moderna to screw up everyone's DNA here, no problem. Yes, I'm still glad that I got the J&J, older tech is better than new.[/QUOTE]Sure, I agree, who needs progress in health care? I would advocate going back to the times where dentistry was performed as a moonlighting job by skilled butchers. That was the real dentistry experience, not the sissy one we have today, full of anesthetics and low pain procedures.
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[QUOTE=Pistons;2551051]That's what I said! And they always have been!
Though the amateurs in here have advocated otherwise.
Or wait? Are they actually changing their minds too now?[/QUOTE]6 cases of thrombosis in 6.8 millions doses given (I. E. Ultra rare adverse events):
[URL]https://www.fda.gov/news-events/press-announcements/joint-cdc-and-fda-statement-johnson-johnson-covid-19-vaccine[/URL]
If you think this is a disaster, I would advise you not to take any medicine for the rest of your life.