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Senior Member
Posts: 334
What I heard was Chloroquine was more effective at early stages but once the person is in the later stages it did not prove to be effective. So gee. You think we should have had our testing shit in gear?
We can't even take advantage of the drugs we find helpful in a meaningful way.
Originally Posted by Travv
[View Original Post]
Background: Severe acute respiratory syndrome (SARS) is caused by a newly discovered coronavirus (SARS-CoV). No effective prophylactic or post-exposure therapy is currently available.
Results: We report, however, that chloroquine has strong antiviral effects on SARS-CoV infection of primate cells. These inhibitory effects are observed when the cells are treated with the drug either before or after exposure to the virus, suggesting both prophylactic and therapeutic advantage. In addition to the well-known functions of chloroquine such as elevations of endosomal pH, the drug appears to interfere with terminal glycosylation of the cellular receptor, angiotensin-converting enzyme 2. This may negatively influence the virus-receptor binding and abrogate the infection, with further ramifications by the elevation of vesicular pH, resulting in the inhibition of infection and spread of SARS CoV at clinically admissible concentrations.
Conclusion: Chloroquine is effective in preventing the spread of SARS CoV in cell culture. Favorable inhibition of virus spread was observed when the cells were either treated with chloroquine prior to or after SARS CoV infection. In addition, the indirect immunofluorescence assay described herein represents a simple and rapid method for screening SARS-CoV antiviral compounds.
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Senior Member
Posts: 1949
Originally Posted by WombatEd2
[View Original Post]
A lot of us don't want to die from the virus. Or give it to someone else who would die.
Give the doom and gloom a rest already. You should sense from responses to your posts in the various Tijuana threads that people are tired of your act.
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Regular Member
Posts: 1
Originally Posted by Dogers69
[View Original Post]
I think tijuana bars restaurants will open by June 1 to 15th. If hk is not open within a week or two from then, then I'd guess it won't open for many many months. If someone in mexico with leverage decides it's good opportunity to end prostitution for a little while, or long while, or forever they will jump on this opportunity. That's how everything is going in the states, everyone's using the covid to get what they always wanted. But mexico needs money they will look at the truth, the stats, and decide based on real world data, unlike usa which uses emotion. Mexico doesn't have the $$ to stay closed just for emotional comfort. The data tells us, cures, vaccines are years off, hospitals have plenty respirators, this disease won't vanish from hiding, the death rate is around 1 in 700 who get the disease, half will be nursing home aged people. That's not high enough death rate to keep any country closed unless its rich like USA thinks it is.
Your point about leverage reminds me of when Club Help got closed in Rio. You'd never think a cash cow like Help could suddenly close but this happened before the Olympics came to Rio. I'm guessing that the Olympics provided a stronger financial incentive (such as corporate sponsorship) for Rio to change its image as a sex tourism destination.
I'm not sure if Tijuana has any circumstance that incentivizes a change in scenery so to speak. But I could be wrong because I know very little about Tijuana and its political landscape.
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Regular Member
Posts: 2344
Originally Posted by Dogers69
[View Original Post]
The data tells us, cures, vaccines are years off, hospitals have plenty respirators, this disease won't vanish from hiding, the death rate is around 1 in 700 who get the disease, half will be nursing home aged people. That's not high enough death rate to keep any country closed unless its rich like USA thinks it is.
I'm not sure what you are saying here, but you seem to be giving a clearly wrong statistic. The Death Rate is not around 1 in 700 but instead much worse and more deadly. Probably more like 1 in 10 or 1 in 20 who show up at the hospital infected, will not survive.
There are already 63,733 dead in the United States. Try to apply the 1 in 700 statistic. It would mean there was 44,613,100 people infected in the United States, and that would grow as the death rate rose.
I agree that the 1. 1 million confirmed coronavirus cases in the United States is an under count of the real number of infected American residents. But that number is not as high as 44 million (1 in 7).
12,500 people have died in New York City. That does not mean there are 8,750,000 infected people in the Big Apple. Hell, in year 2018 their total population was only 8.4 million!
More like 1 in 20, not 1 in 700.
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Senior Member
Posts: 1479
Originally Posted by Rainman306
[View Original Post]
When is your best guess for Tijuana and all the big bars / strip clubs reopening?
I think by Summer everything will be open.
Booked a flight from Chicago to San Diego in July for less than one session with a bar girl hottie would cost.
I think tijuana bars restaurants will open by June 1 to 15th. If hk is not open within a week or two from then, then I'd guess it won't open for many many months. If someone in mexico with leverage decides it's good opportunity to end prostitution for a little while, or long while, or forever they will jump on this opportunity. That's how everything is going in the states, everyone's using the covid to get what they always wanted. But mexico needs money they will look at the truth, the stats, and decide based on real world data, unlike usa which uses emotion. Mexico doesn't have the $$ to stay closed just for emotional comfort. The data tells us, cures, vaccines are years off, hospitals have plenty respirators, this disease won't vanish from hiding, the death rate is around 1 in 700 who get the disease, half will be nursing home aged people. That's not high enough death rate to keep any country closed unless its rich like USA thinks it is.
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Senior Member
Posts: 536
Testy? You Bet!
Originally Posted by DickusMaximus
[View Original Post]
A lot of you are very testy and have nothing to do but argue about politics. I suggest going and taking advantage of the sure-to-be-had deals.
A lot of us don't want to die from the virus. Or give it to someone else who would die.
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Regular Member
Posts: 2344
Originally Posted by Rainman306
[View Original Post]
When is your best guess for Tijuana and all the big bars / strip clubs reopening?
I think by Summer everything will be open.
Booked a flight from Chicago to San Diego in July for less than one session with a bar girl hottie would cost.
The government announced on April 16 that it will restrict transportation between areas of the country that are infected with COVID-19 (mostly large cities) and areas that are not infected, without specifying what areas are included or how it will be enforced. President Lpez Obrador also said that based upon current projections, the 979 municipalities that have not had reported cases of coronavirus will be able to reopen schools and workplaces on May 17; the date is June 1 for the 463 municipalities that have. The elderly and other vulnerable groups will still be requested to stay home, and physical distancing should remain in place until May 30. It is expected that the pandemic will end in the metropolitan area on June 25th.
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Senior Member
Posts: 155
Went down today to see my regular. Was not stopped or asked questions by MX border agents on the way down by auto through San Ysidro. Returned through Otay Mesa SENTRI, asked "Where are you going?" and "Do you have anything to declare?" Wait time was approximately 2 minutes. Ready lane was reported at about 100 minutes. Passed by a few love motels. Those that didn't have enclosed garages looked busy. Called Motel Via a few days ago and was told they were operating and no problems if foreigners wanted to stay there.
A lot of you are very testy and have nothing to do but argue about politics. I suggest going and taking advantage of the sure-to-be-had deals.
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Senior Member
Posts: 248
Reopening of Tijuana -- Best Guess
When is your best guess for Tijuana and all the big bars / strip clubs reopening?
I think by Summer everything will be open.
Booked a flight from Chicago to San Diego in July for less than one session with a bar girl hottie would cost.
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Senior Member
Posts: 1479
Originally Posted by Jinxx
[View Original Post]
She lived in Mexico and she worked as a physical education teacher at a primary school in Ciudad Juarez. Teachers in the US barely make enough to survive so I can imagine what a primary school PE teacher in Mexico makes, probably less than the US minimum wage.
How in the world did you come to the conclusion that "it just sounded like they liked Mexico"? Huh? What? We're not talking about white sandy beaches of Cancun or Cabo San Lucas. Ciudad Juarez is an ugly ass, mega dangerous, semi war zone, hell hole. This guy is a good looking guy with money. He was only in Juarez to be with her, because that's her home, and they were quarantining together.
And yes I'm thinking that there's a good chance that she has a "prior boyfriend" with big dinero who paid for her fancy vacations. And whether he was a narco or not, it's probably not difficult for a jealous local guy with money to arrange a hit on some outsider who's in town shacked up with his gorgeous ex novia.
I had read only 1 article and it said she was from Texas. But ok so he was in mexico for her. Not a good move. Probably he wasnt well read up on Juarez crime news. But plenty people go to Tijuana to check it out, I see them on the trolley. Tijuana is it's own nightmare. 2018 was the most deadly city in the world. Not sure who won 2019. Tijuana elementary school teachers make enough to rent a house have internet cell phones do uber and raise 3 kids without a baby daddy help. And qualify for visa to USA. So they must make at least 20 k. Teachers in nyc suburbs make 140 grand. I know they were making 120 grand 20 years ago. For all I know it's up to 160 grand. But has to be up to 135 grand minimum. That's without doing after school teams etc. Those types easily hit 160 grand.
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Regular Member
Posts: 657
Chloroquine is a potent inhibitor of SARS coronavirus infection and spread.
Background: Severe acute respiratory syndrome (SARS) is caused by a newly discovered coronavirus (SARS-CoV). No effective prophylactic or post-exposure therapy is currently available.
Results: We report, however, that chloroquine has strong antiviral effects on SARS-CoV infection of primate cells. These inhibitory effects are observed when the cells are treated with the drug either before or after exposure to the virus, suggesting both prophylactic and therapeutic advantage. In addition to the well-known functions of chloroquine such as elevations of endosomal pH, the drug appears to interfere with terminal glycosylation of the cellular receptor, angiotensin-converting enzyme 2. This may negatively influence the virus-receptor binding and abrogate the infection, with further ramifications by the elevation of vesicular pH, resulting in the inhibition of infection and spread of SARS CoV at clinically admissible concentrations.
Conclusion: Chloroquine is effective in preventing the spread of SARS CoV in cell culture. Favorable inhibition of virus spread was observed when the cells were either treated with chloroquine prior to or after SARS CoV infection. In addition, the indirect immunofluorescence assay described herein represents a simple and rapid method for screening SARS-CoV antiviral compounds.
https://www.ncbi.nlm.nih.gov/pubmed/16115318
Nutshell: Chloroquine has been known since 2005 to be "a potent inhibitor of Sars Coronavirus. . . " NIH: Director About NIAID Director, Anthony Fauci, M. The.
https://www.niaid.nih.gov/about/anthony-s-fauci-md-bio
Originally Posted by WombatEd2
[View Original Post]
If this was anything other than quack science, it would be covered by at least one reliable news source, but according to Google, not so much.
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Senior Member
Posts: 536
Some Blogger On the InterNutz Says.
Originally Posted by Travv
[View Original Post]
Media lied, people died: Italian study finds incredible. Prophylaxis Results for Patients on Hydroxychloroquine.
And now a new study from hard-hit Italy found that those Italians on hydroxychloroquine for Lupus or Rheumatoid Arthritis did not come down with the coronavirus. Only 20 patients (out of 65000) tested positive for COVID-19. No ICU, and no one died!
Via Dr. James Todara, MD.
https://www.thegatewaypundit.com/202...sharingbuttons
I've been taking HCQ for about 5 weeks per the Indian Ministry of Health Council reco for doctors treating COVID patients plus zinc daily. So I'm taking trips to Tijuana without worries about getting the China fever. Have visited farmacias in Tijuana to buy more HCQ and now it is much more difficult, likely due to hoarding by pharmacists and doctors.
If this was anything other than quack science, it would be covered by at least one reliable news source, but according to Google, not so much.
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Senior Member
Posts: 106
The Border
Contrary to my previous report, crossing north at San Ysidro no longer has the fast window at midnight. Dunno what happened, but just sat through a 2 hour wait at approximately the same time frame where a month ago took less than 3 minutes. BWT websites, both app and Chrome showed an increase where they're normally conservative estimates. YMMV. A real crapshoot.
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Regular Member
Posts: 657
Media lied, people died: Italian study finds incredible Prophylaxis Results for HCQ
Media lied, people died: Italian study finds incredible. Prophylaxis Results for Patients on Hydroxychloroquine.
And now a new study from hard-hit Italy found that those Italians on hydroxychloroquine for Lupus or Rheumatoid Arthritis did not come down with the coronavirus. Only 20 patients (out of 65000) tested positive for COVID-19. No ICU, and no one died!
Via Dr. James Todara, MD.
https://www.thegatewaypundit.com/202...sharingbuttons
I've been taking HCQ for about 5 weeks per the Indian Ministry of Health Council reco for doctors treating COVID patients plus zinc daily. So I'm taking trips to Tijuana without worries about getting the China fever. Have visited farmacias in Tijuana to buy more HCQ and now it is much more difficult, likely due to hoarding by pharmacists and doctors.
Originally Posted by WombatEd2
[View Original Post]
People with the virus are contagious for several days before they show any symptoms.
So if the SA gal is infected, so are you.
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Senior Member
Posts: 536
Originally Posted by TjBrazil
[View Original Post]
The virus shouldn't matter if use SA. They just drive to your hotel. What am I missing.
People with the virus are contagious for several days before they show any symptoms.
So if the SA gal is infected, so are you.
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